Chili Extract

1. Antibacterial effect：Capsaicin has a significant inhibitory effect on Bacillus cereus and Bacillus subtilis, but is ineffective against Staphylococcus aureus and Escherichia coli.

2. Antioxidant effect: Capsaicin has strong antioxidant capacity, which helps to delay cell aging and prevent various diseases.

3. Promote metabolism: Capsaicin can alleviate inflammatory reactions in adipose tissue, improve insulin resistance, and further reduce lipid metabolism

 

 

The applications of synthetic capsaicin are very broad, covering multiple industries and uses. The following are detailed descriptions of the main application areas:

Medical field

Medical research and pharmacological clinical experiments show that capsaicin has significant effects on herpes zoster neuralgia, surgical neuralgia, diabetes and other diseases.

Food additive

As a functional food additive, capsaicin can dispel wind and blood, dispel cold and depression, relieve stagnation and pain, stop addiction and eczema, and promote appetite and improve digestion.

Pesticide

Capsaicin, as a plant derived pesticide, has received widespread attention due to its low toxicity, safety, and multiple biological activities. It is used to manufacture pollution-free biochemical pesticides, such as products that repel aphids and mites.

Chemical coatings

Capsaicin is used to manufacture functional plastic pellets and coatings that prevent termites and mice, for use in cable, underground building, and civil furniture manufacturing industries.

Military use

Capsaicin is also widely used in the military field, such as as as a rodent repellent and repellent.

Synthetic capsaicin extract not only has a wide range of pharmacological effects and versatility, but also shows great application potential in many fields. With the progress of extraction technology, its application scope and economic benefits will be further improved.

The specific production details of synthetic capsaicin extract involve many steps and methods, including pre-treatment, extraction, impurity removal and crystallization. The following is the detailed production process:

1. Pre-treatment:

dry red pepper powder for preliminary treatment, such as crushing and mixing, to ensure the uniformity of chili powder.

 

2. Extraction:

A,Organic solvent extraction method:

ethanol, ethyl ether, acetone, petroleum ether, ethyl acetate, etc. are used as the extraction agent. For example, a higher extraction rate of capsaicin could be obtained by using 70% ethanol as solvent in a constant temperature water bath at 58℃ for 4 hours with a solid-liquid ratio of 1:11.

 

B,Supercritical CO2 fluid extraction method:

supercritical CO2 extraction is carried out under the conditions of pressure of 20 ~ 30MPa and temperature of 35 ~ 45℃, and the extraction time is 2 ~ 3 hours, and capsaicin with high purity and less impurities can be obtained.

C,Microwave and ultrasonic assisted extraction method:

Enhanced extraction effect by microwave or ultrasonic, such as 70% ethanol and ultrasonic power 60W extraction at 70℃, can improve the extraction rate of capsaicin.

D,Enzyme extraction method:

The use of specific enzymes in the appropriate pH and temperature conditions for enzymatic hydrolysis, such as the initial pH5.5, enzyme amount of 9mg/g, enzymatic hydrolysis time 1 hour, enzymatic hydrolysis temperature 40℃ under the conditions of enzymatic hydrolysis, can get a higher extraction rate of capsaicin.

3. Impurity removal:

A,Organic solvents such as petroleum ether and ether are used for phase separation to remove impurities. For example, after the extract is dissolved with 2%NaOH, the organic phase and the aqueous phase are separated by petroleum ether extraction.

B,The crude extract was preliminarily purified by resin method, and the purity of capsaicin was improved after solvent recovery.

 

4. Crystallization:

The purified capsaicin solution is heated to a certain temperature, then the crystallization is cooled, filtered and dried to obtain high-purity capsaicin crystals.

5. Optimization process:

The extraction conditions were optimized by single factor test and orthogonal test, such as determining the optimal extraction solvent concentration, temperature, time and solid-liquid ratio to improve the extraction rate and purity of capsaicin.

In summary, the specific production details of synthetic capsaicin extract include pre-treatment, organic solvent extraction, supercritical CO₂ fluid extraction, microwave and ultrasonic assisted extraction, enzyme extraction, impurity removal, resin purification and crystallization. By optimizing these process conditions, high yield and high purity capsaicin extraction can be achieved.